PDE5 inhibitors – Common Erectile Dysfunction Drugs

These medications aid in the erection of the penis. They make it easier to get and keep erections, but they still require sexual stimulation to work.

PDE5 inhibitors operate by allowing blood arteries that supply your penis to open up. This boosts your erection by increasing blood flow to your penis. They may not work in cases of severe Erectile Dysfunction or irreversible damage to the natural erectile mechanism. More information on erectile dysfunction can be found here.

PDE5 inhibitors are most effective when used in conjunction with other lifestyle changes such as weight loss, increased physical activity, and stopping smoking, obtaining enough sleep, and reducing alcohol consumption. All of these factors can have a significant impact on erectile dysfunction. The libido (sexual desire), ejaculation, and fertility are unaffected by PDE5 inhibitors.

Is There a Difference Between PDE5 Drugs and other Inhibitors?

PDE5 inhibitors (sildenafil, tadalafil, and vardenafil) are all effective in the same way. They are effective for the majority of men with erectile dysfunction, permitting intercourse (or sex) in roughly 70% (7 out of 10) of users. Tadalafil can be take with or without food; however sildenafil and vardenafil must be take on an empty stomach.

What is the Best way to take a PDE5 Inhibitor?

Timing is Everything

A tablet should be taken 30 minutes to 1 hour before sexual intercourse; depending on the prescription you’ve been prescribe. To get an erection, you still need to use your hands. The medication should be uses in a calm environment.

It could be Influenced by what you eat

Fatty foods and a lot of alcohol can make it difficult for the body to absorb these medications. Due to delay absorption from meals, sildenafil and vardenafil must be take on an empty stomach, whereas tadalafil does not.

Is it okay if I take it every day

It’s generally not a good idea to take more than one regular dose in a 24-hour period, although there are low-dose choices that can be taken every day. For persons who have intercourse more than twice a week, the daily low-dose option is employ. When you are sexually stimulate, it will induce an erection. Because the dose is smaller, it may take up to a week for the drug to take full action after you start taking it.

PDE5 Inhibitors aren’t Appropriate for Everyone.

PDE5 inhibitors should be uses only after a thorough medical assessment for men with cardiovascular disorders such as coronary heart disease (CHD), myocardial insufficiency, and cardiac arrhythmia. Patients with thrombosis, heart attack, or stroke in their anamnesis are in the same boat. First and foremost, it must be determined whether physical activity during sex is bearable – or whether it may cause the heart to overwork.

When are PDE5 Inhibitors not Recommended?

The use of PDE5 inhibitors is not recommend for everyone. If you have certain medical conditions, such as a recent stroke, unstable angina, or myocardial infarction, or if your blood pressure is not properly regulate, they may not be safe.

If you’re taking any drugs, you shouldn’t utilize PDE5 inhibitors. PDE5 inhibitors and nitrates (e.g., GTN spray or isosorbide mononitrate), which are use to treat chest pain and other heart diseases, should not be taken together since they might cause a hazardous drop in blood pressure and collapse.

Before you start taking a PDE5 inhibitor, ask your doctor or pharmacist to verify all of the other medications you’re taking to be sure they’re compatible.

What are the PDE5 Inhibitors’ Adverse Effects?

The most common adverse effects are headache (12%), flushing (10%), and indigestion (10%). (7%). Some persons experience dizzy and have blue-tinged eyesight (3%). If you have dizziness, do not drive or operate heavy machinery.

Any serious side effect should be report to your doctor or pharmacist.

What is the Best way to Obtain PDE5 Inhibitors?

Your doctor can prescribe sildenafil, tadalafil, or vardenafil for you. In New Zealand, none of the drugs for general erectile dysfunction are cover. Generic alternatives are typically less expensive than branded alternatives and perform similarly (eg, Silvasta or Vedafil instead of Viagra).

After consulting with a pharmacist, you can purchase sildenafil straight from select pharmacies. Sildenafil is only available from pharmacists who have completed further training. They’ll take your blood pressure and ask your questions to make sure it’s safe for you (such as what other medicines you are taking). They’ll need to take down your name and address as well.

What Should I do if PDE5 Inhibitors don’t Work for me?

PDE5 inhibitors do not work for everyone; approximately 30% of men do not notice a difference. Many men must try the medicine several times (6–8) before it succeeds. If you haven’t had sex in a long time, you may experience some nervousness the first few times you use these drugs.

Do not raise your dose if you do not notice any improvement. Instead, consult your physician. Other therapy options may be available.