Seroquit 25 mg (Quetiapine)

What is Seroquit 25 mg?

Seroquit 25 mg contains Quetiapine, an atypical antipsychotic medication. It is commonly used to treat mental health conditions by altering the effects of neurotransmitters in the brain, primarily dopamine and serotonin.

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What are the Uses of Seroquit 25 mg?

Seroquit is prescribed for the treatment of:

• Schizophrenia

• Bipolar Disorder (mania and depression)

• Major Depressive Disorder (MDD) – as an adjunct therapy

• Generalized Anxiety Disorder (off-label)

• Insomnia (off-label and short-term)

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What are the Benefits of Seroquit 25 mg?

• Reduces hallucinations and delusions in schizophrenia

• Stabilizes mood swings in bipolar disorder

• Improves sleep and reduces anxiety

• Helps in managing aggression, agitation, and psychotic symptoms

• Can boost effectiveness of antidepressants when used as adjunct therapy

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How Does Seroquit 25 mg Work?

Seroquit (Quetiapine) works by:

• Modulating neurotransmitter activity to balance mood and reduce psychotic symptoms

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How to Take Seroquit 25 mg?

• Take once or twice daily, with or without food

• Swallow the tablet whole with water

• Take at the same time daily for best results

• Avoid alcohol and grapefruit juice during treatment

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Dosage of Seroquit 25 mg

• Starting Dose: Often begins at 25 mg/day for psychiatric conditions

• Titration: Doctor may gradually increase the dose based on condition and response

• Maintenance Dose: May range between 150 mg to 800 mg/day in divided doses

• Follow exact dosage as directed by your healthcare provider

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Missed Dose and Overdose

• Missed Dose: Take it as soon as remembered. Skip if near next dose. Do not double dose.

• Overdose: Can cause severe drowsiness, low blood pressure, irregular heartbeat, or coma. Seek emergency medical attention immediately.

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Available Strengths of Seroquit

• Seroquit 25 mg

• Seroquit 50 mg

• Seroquit 100 mg

• Seroquit 200 mg

• Seroquit 300 mg

• Seroquit 400 mg

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Side Effects of Seroquit 25 mg

Common Side Effects:

• Drowsiness or sedation

• Dizziness or lightheadedness

• Weight gain

• Dry mouth

• Constipation

• Increased appetite

Serious Side Effects:

• High blood sugar (hyperglycemia)

• Cholesterol increase

• Low white blood cell count

• Tardive dyskinesia (uncontrollable movements)

• Neuroleptic Malignant Syndrome (rare but life-threatening)

• Suicidal thoughts (especially in younger patients)

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Interactions of Seroquit 25 mg

Avoid combining with:

• CNS depressants (e.g., benzodiazepines, opioids)

• Antifungals (e.g., ketoconazole, increase quetiapine levels)

• Certain antibiotics, antivirals, and seizure medications

• Grapefruit juice (alters drug metabolism)

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Precautions for Seroquit 25 mg

• Not recommended for dementia-related psychosis (risk of death)

• Use caution in patients with diabetes, cardiovascular issues, or seizure disorders

• Monitor blood sugar, lipid profile, and weight

• Can cause orthostatic hypotension (sudden blood pressure drop)

• Avoid in pregnancy and breastfeeding unless clearly indicated

• Taper gradually when discontinuing

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Storage Information

• Store at room temperature (15–30°C)

• Keep away from moisture, light, and heat

• Keep out of reach of children

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Availability in the US and Australia

• In the US, Quetiapine is available under the brand Seroquel and generics (e.g., Quetiapine Fumarate)

• In Australia, available via prescription under Seroquel or as generic Quetiapine

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Frequently Asked Questions 

1. Can Seroquit 25 mg be used for sleep?

Yes, due to its sedative effects, it’s sometimes used off-label for insomnia. However, long-term use solely for sleep is discouraged.

2. Is Seroquit addictive?

No, but sudden discontinuation can cause withdrawal symptoms such as insomnia, nausea, and anxiety. Tapering is advised.

3. Can it cause weight gain?

Yes, weight gain and increased appetite are common side effects, especially with prolong use.

4. How long does it take to work?

Sleep and sedation effects may occur within hours. For mood or psychotic symptoms, it may take 1 to 2 weeks or more.