Fenbendazole 444 mg

What is Fenbendazole 444 mg?

Fenbendazole 444 mg is a broad-spectrum antiparasitic (anthelmintic) medication commonly used in veterinary medicine to treat and control intestinal parasites in animals, particularly dogs. It belongs to the benzimidazole class of drugs and is often used off-label for other purposes, including in experimental human cancer research, although this is not FDA-approved.

Uses of Fenbendazole 444 mg

Fenbendazole 444 mg is primarily used to:

• Treat intestinal worms such as:

  • Roundworms

  • Hookworms

  • Whipworms

  • Tapeworms (excluding Dipylidium caninum)

• Control parasitic infestations in pets, especially dogs and cats

• Occasionally used for livestock and other domestic animals

⚠️ Note: Its use in humans is experimental and not officially approved by regulatory bodies like the FDA.

Benefits of Fenbendazole 444 mg

• Effective against a broad range of parasites

• Generally safe and well-tolerated in animals

• Helps maintain intestinal health and hygiene in pets

• May contribute to improved appetite, energy, and health in treated animals

• Easy administration – available in granule, tablet, and liquid form

How Does Fenbendazole 444 mg Work?

Fenbendazole works by inhibiting the formation of microtubules in parasitic cells. It interferes with the parasite’s ability to absorb glucose, leading to energy depletion, immobilization, and death. The drug selectively targets parasite cells, making it safer for the host animal.

How to Take Fenbendazole 444 mg?

• Usually administered orally, often mixed with food.

• Available as granules, tablets, or suspension.

• Follow veterinarian guidance for correct dosage and treatment duration.

• Treatment may last 3–5 consecutive days, depending on the infestation.

Dosage of Fenbendazole 444 mg

• Standard dosage: One 444 mg packet per 40 lb (18.2 kg) of body weight, once daily for 3 consecutive days.

• Dosage may vary based on:

  • Type of parasite

  • Animal’s size and weight

  • Severity of infestation

Always consult a veterinarian for accurate dosing.

Missed Dose and Overdose

Missed Dose:

• Give the missed dose as soon as remembered.

• If it’s almost time for the next dose, skip the missed dose.

• Do not double dose to make up for the missed one.

Overdose:

• Overdose is rare but may cause:

  • Vomiting

  • Diarrhea

  • Salivation

• Seek immediate veterinary attention if overdose is suspected.

Available Strengths of Fenbendazole

• Common strengths include:

  • 222 mg

  • 444 mg

  • 888 mg

• Often sold under brand names like Panacur®, Safe-Guard®, or generically.

Side Effects of Fenbendazole 444 mg

While generally safe, side effects may include:

• Mild diarrhea

• Vomiting

• Temporary loss of appetite

• Lethargy

• Rare allergic reactions

Most side effects are mild and resolve on their own.

Interactions of Fenbendazole 444 mg

Fenbendazole has low potential for drug interactions, but caution is advised if the pet is also receiving:

• Other anthelmintics

• Medications affecting liver enzymes

• Supplements or off-label cancer treatments

Always inform your vet about any other medications or supplements your pet is taking.

Precautions of Fenbendazole 444 mg

• Use only in animals; not approved for human use

• Use with caution in pregnant or lactating animals

• Ensure accurate dosing by weight

• Complete the full treatment course to prevent resistance

• Do not use in animals with known hypersensitivity to benzimidazoles

Storage Information

• Store at room temperature (15–30°C / 59–86°F)

• Keep in a dry place, away from moisture and sunlight

• Keep out of reach of children and pets

Availability in the US and Australia

United States:

• Widely available in pet stores, veterinary clinics, and online

• Sold under brand names such as:

  • Panacur C

  • Safe-Guard Canine Dewormer

Australia:

• Available via veterinary prescription or over-the-counter

• Marketed for livestock and pets

• May be subject to stricter controls for off-label use

Frequently Asked Questions (FAQs)

1. Is Fenbendazole safe for all dogs?

Yes, it’s generally safe, but consult your vet for dogs with existing health conditions or those on other medications.

2. Can I give Fenbendazole to cats or other animals?

Some formulations may be suitable for cats or livestock, but always check species-specific dosing.

3. Can humans take Fenbendazole?

No. Its use in humans is not FDA-approved and should be avoided outside clinical research setting.

4. How long does it take for Fenbendazole to work?

You may see improvement within a few days, but the full course (usually 3 days) should be completed.

5. Does it prevent future worm infestation?

It treats existing infestations but does not prevent reinfection. Regular deworming is recommend.