Doverin 40 mg (Drotaverine)

What is Doverin 40 mg (Drotaverine)?

Doverin 40 mg contains Drotaverine, a muscle relaxant and antispasmodic medication used to relieve smooth muscle spasms. It is commonly prescribe for abdominal, gastrointestinal, urinary, and gynecological pain caused by spasms or contractions.

Drotaverine is a non-atropine, non-narcotic antispasmodic, making it a preferred choice for patients sensitive to atropine-based medications.

Uses of Doverin 40 mg

Doverin 40 mg is used for treating:

• Abdominal pain and cramps

• Irritable bowel syndrome (IBS)

• Biliary colic (gallbladder-related pain)

• Renal colic (kidney stone pain)

• Menstrual cramps (dysmenorrhea)

• Spastic constipation

• Postoperative or post-labor uterine spasms

Benefits of Doverin 40 mg

• Rapid pain relief from smooth muscle spasms

• Non-sedative and non-narcotic — doesn’t cause dependence

• Well-tolerated in both gastrointestinal and gynecological conditions

• Suitable for long-term and short-term use under medical supervision

How Does Doverin 40 mg Work?

Drotaverine works by inhibiting the phosphodiesterase-4 (PDE-4) enzyme, which increases levels of cyclic AMP (cAMP) in smooth muscle cells. This leads to relaxation of smooth muscle fibers, helping reduce spasms in the gastrointestinal, urinary, or reproductive systems. Unlike other antispasmodics, it does not affect the autonomic nervous system.

How to Take Doverin 40 mg

• Take orally with or without food.

• Swallow the tablet with a full glass of water.

• Do not crush or chew the tablet unless advised.

• Follow your doctor’s prescribed schedule.

Dosage of Doverin 40 mg

Typical adult dosage:

• 40–80 mg (1–2 tablets) taken 2–3 times daily, depending on the severity of symptoms.

• Maximum daily dose: 240 mg (usually not exceede without medical supervision).

Missed Dose and Overdose

• Missed Dose: Take it as soon as you remember. If it’s almost time for the next dose, skip the missed one. Do not double the dose.

• Overdose: In case of overdose, symptoms may include:

  • Nausea, vomiting

  • Low blood pressure

  • Dizziness or collapse

  • Irregular heartbeat
    Seek immediate medical attention if overdose is suspected.

Available Strengths of Doverin (Drotaverine)

• Doverin 40 mg tablets

• Doverin 80 mg tablets

• Drotaverine injection (for clinical or hospital use)

Side Effects of Doverin 40 mg

Common side effects:

• Nausea

• Dizziness

• Headache

• Dry mouth

Rare but serious side effects:

• Low blood pressure

• Allergic reactions (rash, itching, swelling)

• Palpitations or irregular heartbeat

Most side effects are mild and temporary. Report any persistent or severe symptoms to your doctor.

Interactions of Doverin 40 mg

Use caution if taking with:

• Levodopa (may reduce the effectiveness of Parkinson’s treatment)

• Antihypertensives (may enhance blood pressure-lowering effects)

• Other antispasmodics or muscle relaxants

Always inform your doctor of any other medications, herbal supplements, or over-the-counter drugs you are using.

Precautions of Doverin 40 mg

• Not recommended for:

  • Severe liver, kidney, or heart failure

  • Children under 1 year (unless prescribe by a pediatrician)

• Use with caution in:

  • Pregnancy and breastfeeding (consult a doctor)

  • Patients with low blood pressure

• Do not operate heavy machinery if you feel dizzy after taking the medication.

Storage Information

• Store at room temperature (15–30°C).

• Keep away from moisture, heat, and direct sunlight.

• Keep out of reach of children.

• Do not use if the tablet is discolored or damaged.

Availability in the US and Australia

• United States: Drotaverine (Doverin) is not FDA-approved and is generally not available.

• Australia: Not approve by the TGA and not widely available through pharmacies.

• Alternative antispasmodics like Hyoscine (Buscopan) or Dicyclomine are more commonly used in these countries.

Frequently Asked Questions (FAQs)

Q1: Is Doverin the same as Drotaverine?

Yes, Doverin is a brand name for the active ingredient Drotaverine.

Q2: Can I take Doverin during pregnancy?

Only under strict medical supervision, especially in the second and third trimesters. Not advised in early pregnancy unless absolutely necessary.

Q3: Does Doverin cause drowsiness?

It is generally non-sedative, but some people may experience mild dizziness.

Q4: Can it be used for menstrual cramps?

Yes, it is commonly prescribe for primary and secondary dysmenorrhea.

Q5: Is it safe to use with other painkillers?

Yes, but only under medical advice. It may be used with paracetamol or NSAIDs for enhance relief.