Pregabalin 75 mg

What is Pregabalin 75mg?

Pregabalin 75mg is a prescription medication used to treat neuropathic pain, epilepsy, fibromyalgia, and generalized anxiety disorder (GAD) in some countries. It belongs to a class of medications known as anticonvulsants or neuropathic pain agents.

Common brand names include Lyrica, and it may also be sold under various generic names globally.

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What are the Uses of Pregabalin 75mg?

Pregabalin 75 mg is prescribed for the following medical conditions:

• Neuropathic pain due to diabetes (diabetic neuropathy), shingles (postherpetic neuralgia), or spinal cord injury

• Partial-onset seizures (adjunct therapy in epilepsy)

• Fibromyalgia (widespread muscle pain and tenderness)

• Generalized Anxiety Disorder (GAD) (approved in some regions)

• Restless Legs Syndrome (off-label use)

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What are the Benefits of Pregabalin 75mg?

• Reduces nerve pain intensity and improves quality of life

• Helps control seizures in people with epilepsy

• Improves sleep and reduces anxiety symptoms

• Enhances daily functioning in patients with chronic pain or fibromyalgia

• Offers rapid onset of action (often within a week)

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How Does Pregabalin 75 mg Work?

Pregabalin works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces the release of several neurotransmitters (e.g., glutamate, norepinephrine, substance P), helping to stabilize overactive nerves, relieve pain, and control seizures.

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How to Take Pregabalin 75 mg?

• Take the capsule orally, with or without food.

• Swallow it whole with a glass of water.

• Take it at the same time each day for best results.

• Follow your healthcare provider’s instructions carefully—do not self-adjust the dose.

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Dosage of Pregabalin 75 mg

• Starting dose: Often 75 mg twice daily (150 mg/day), especially for neuropathic pain.

• Maintenance dose: Can be increased to 150–600 mg/day, in divided doses based on response.

• Seizure treatment: Dosage varies, often 150–600 mg/day as adjunct therapy.

• Dose adjustments may be required in patients with kidney impairment.

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Missed Dose and Overdose

Missed Dose:

• Take it as soon as you remember.

• If it’s close to the next scheduled dose, skip the missed dose—do not double it.

Overdose:

• Symptoms: Severe drowsiness, confusion, agitation, seizures

• Contact emergency services or a poison control center immediately.

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Available Strengths of Pregabalin

Pregabalin is available in multiple strengths:

• 25 mg

• 50 mg

• 75 mg

• 100 mg

• 150 mg

• 200 mg

• 225 mg

• 300 mg

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Side Effects of Pregabalin 75 mg

Common Side Effects:

• Dizziness

• Drowsiness or fatigue

• Dry mouth

• Weight gain

• Blurred vision

• Difficulty concentrating

• Swelling in hands or feet

Serious Side Effects:

• Mood changes, depression, suicidal thoughts

• Allergic reactions (rash, itching, swelling, trouble breathing)

• Muscle pain or weakness

• Vision changes

Seek medical attention if you experience serious or persistent side effects.

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Interactions of Pregabalin 75 mg

Pregabalin may interact with:

• Alcohol and CNS depressants (e.g., opioids, sedatives): increases sedation risk

• Antidepressants: additive effects on mood and nervous system

• Diabetes medications: may enhance peripheral edema

• Other anticonvulsants: may require dose adjustments

Always inform your doctor about all medications and supplements you are taking.

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Precautions of Pregabalin 75 mg

• Avoid alcohol and operating heavy machinery until you know how it affects you.

• Use with caution in patients with renal impairment—dose modification required.

• Not recommend during pregnancy or breastfeeding unless clearly necessary.

• Taper off slowly under medical supervision to prevent withdrawal symptoms.

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Storage Information

• Store in a cool, dry place at 15–25°C (59–77°F).

• Protect from moisture and direct sunlight.

• Keep out of reach of children and pets.

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Availability in the US and Australia

• In the US: Available under the brand name Lyrica and as generic Pregabalin.

• In Australia: Available under Lyrica and various generic brands, prescribed under the Pharmaceutical Benefits Scheme (PBS) for certain conditions.

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Frequently Asked Questions (FAQs)

1. Is Pregabalin 75mg the same as Lyrica?

Yes, Lyrica is a brand name for Pregabalin. The 75 mg formulation is commonly used for nerve pain and epilepsy.

2. Can Pregabalin be used long-term?

Yes, but long-term use should be monitor by a doctor due to potential side effects and risk of dependence.

3. How long does it take for Pregabalin 75 mg to work?

Initial relief may occur within 1 week, with full effects seen over 2–4 weeks.

4. Is Pregabalin addictive?

Pregabalin has some potential for dependence, especially when misused. Take only as prescribe.

5. Can I stop Pregabalin suddenly?

No. Stopping abruptly can cause withdrawal symptoms or worsening of the condition. Always taper off gradually under supervision.