Brufen 400mg (Ibuprofen)

What is Brufen 400mg (Ibuprofen)?

Brufen 400mg is a branded formulation of Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID). It is widely used for the relief of mild to moderate pain, inflammation, and fever. Brufen is available by prescription or over-the-counter, depending on the strength and local regulations.

Uses of Brufen 400mg

Brufen 400mg is used to treat various conditions, including:

• Headaches and migraines

• Dental pain

• Menstrual cramps (dysmenorrhea)

• Musculoskeletal pain (e.g., backache, sprains, strains)

• Arthritis (rheumatoid arthritis, osteoarthritis)

• Fever due to infections or illness

• Minor aches associated with cold or flu

Benefits of Brufen 400mg

• Fast Pain Relief: Typically begins working within 30 minutes

• Anti-inflammatory Action: Reduces swelling and joint inflammation

• Fever Reduction: Helps lower elevated body temperature

• Well-Tolerated: Generally safe when used at recommended doses

• Versatile Use: Effective for a wide range of pain and inflammatory conditions

How Does Brufen 400mg Work?

Ibuprofen, the active ingredient in Brufen 400 mg, works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2). These enzymes play a role in the production of prostaglandins, chemicals responsible for pain, inflammation, and fever. By decreasing prostaglandin levels, Brufen alleviates discomfort and inflammation.

How to Take Brufen 400 mg

• With Food or Milk: Take with meals to reduce stomach irritation

• Swallow Whole: Do not crush or chew the tablet unless advised

• Hydration: Drink a full glass of water with each dose

• Avoid Alcohol: Alcohol can increase the risk of stomach irritation or bleeding

Dosage of Brufen 400 mg

Adults and Children over 12 years:

• Typical dose: 400 mg every 4 to 6 hours as needed

• Maximum daily dose: Do not exceed 3,200 mg per day (usually under medical supervision). For OTC use, limit is often 1,200 mg/day.

Children under 12: Use only under medical advice and with pediatric formulations.

Always follow your healthcare provider’s instructions or the label directions.

Missed Dose and Overdose

• Missed Dose: Take the missed dose when remembered unless it’s close to the next dose. Do not double the dose to catch up.

• Overdose: Symptoms may include nausea, vomiting, stomach pain, drowsiness, headache, dizziness, ringing in the ears, or even seizures. Seek emergency medical help immediately.

Available Strengths of Brufen (Ibuprofen)

Brufen (Ibuprofen) is available in multiple strengths and forms:

• Tablets: 200 mg, 400 mg, 600 mg, 800 mg

• Oral Suspension: For pediatric use

• Effervescent granules, capsules, and gels (depending on country and brand)

Side Effects of Brufen 400 mg

Common Side Effects:

• Nausea or upset stomach

• Indigestion or heartburn

• Headache

• Dizziness

• Rash

Serious Side Effects (seek medical attention):

• Gastrointestinal bleeding or ulcers

• Kidney damage

• Liver issues

• High blood pressure

• Allergic reactions (swelling, difficulty breathing, severe rash)

Interactions of Brufen 400 mg

Ibuprofen may interact with:

• Other NSAIDs (e.g., aspirin, naproxen) – increased risk of ulcers or bleeding

• Anticoagulants (e.g., warfarin) – increased bleeding risk

• Diuretics and ACE inhibitors – reduced effectiveness and risk of kidney damage

• Lithium and methotrexate – increased toxicity

• SSRIs – increased gastrointestinal risk

Inform your doctor of all medications, including over-the-counter and herbal products.

Precautions of Brufen 400mg

• Pregnancy: Avoid in the third trimester unless prescribed

• Breastfeeding: Generally considered safe, but consult a doctor

• Cardiovascular Risk: May increase the risk of heart attack or stroke with long-term use

• Gastrointestinal Risk: Use with caution in patients with ulcers or GI bleeding

• Kidney or Liver Disease: Use only under medical supervision

Storage Information

• Store at 15°C to 30°C (59°F to 86°F)

• Keep away from moisture and direct sunlight

• Keep out of reach of children

• Do not use past the expiration date

Availability in the US and Australia

• United States: Ibuprofen is widely available over-the-counter in 200 mg tablets. Brufen (brand) may not be common, but the same formulation is available under other names like Advil and Motrin.

• Australia: Brufen 400 mg is available by prescription only. Lower strengths (200 mg) may be available OTC.

Frequently Asked Questions (FAQs)

1. Can I take Brufen 400mg on an empty stomach?

It is recommended to take it with food to reduce stomach upset.

2. Is Brufen 400 mg stronger than Panadol (Paracetamol)?

Brufen has anti-inflammatory effects, which paracetamol lacks. It may be more effective for conditions involving inflammation.

3. Can I take Brufen and paracetamol together?

Yes, they can be taken together or alternately for better pain control, but follow medical advice.

4. How long does it take for Brufen 400mg to work?

Usually within 30 to 60 minutes. Peak effect occurs in 1–2 hours.

5. Is Brufen habit-forming?

No, Ibuprofen is not addictive or habit-forming.