Seroquit 50 mg (Quetiapine 50mg)

What is Seroquit 50 mg?

Seroquit 50 mg is a formulation of Quetiapine, an atypical antipsychotic (also known as a second-generation antipsychotic). It is primarily prescribed to manage schizophrenia, bipolar disorder, and major depressive disorder (as adjunct therapy). It may also be used off-label for insomnia and generalized anxiety disorder.

Uses of Seroquit 50 mg

Seroquit 50 mg is used to treat:

• Schizophrenia (delusions, hallucinations, disorganized thinking)

• Bipolar disorder, including:

  • Manic episodes

  • Depressive episodes

  • Maintenance treatment

• Major Depressive Disorder (MDD) — as an add-on to antidepressants

• Off-label uses:

  • Anxiety

  • Insomnia

  • PTSD

Benefits of Seroquit 50 mg

• Reduces hallucinations and delusions

• Improves mood stability and reduces irritability

• Helps manage sleep disturbances

• Enhances response to antidepressants in treatment-resistant depression

How Does Seroquit 50 mg Work?

Quetiapine works by:

• Blocking dopamine D2 and serotonin 5-HT2A receptors, regulating mood and perception

• Interacting with histamine and adrenergic receptors, which contributes to sedation and blood pressure effects

How to Take Seroquit 50 mg

• Take orally, once or twice daily, as prescribed

• Can be taken with or without food

• Swallow tablet whole, do not crush or chew

• Avoid alcohol and grapefruit juice

Dosage of Seroquit 50 mg

• Starting dose for schizophrenia or bipolar disorder: Often starts at 25–50 mg/day, gradually increased

• Maintenance dose: Typically 300–800 mg/day, depending on the condition

• Always follow your doctor’s exact dosing schedule

Missed Dose and Overdose

• Missed Dose: Take it when remembered, but skip if near the next dose. Do not double dose.

• Overdose symptoms:

  • Severe drowsiness

  • Rapid heart rate

  • Low blood pressure

  • Seizures or coma (in extreme cases)

  • Seek immediate medical help

Available Strengths of Seroquit

• 25 mg

• 50 mg

• 100 mg

• 200 mg

• 300 mg

Side Effects of Seroquit 50 mg

Common Side Effects:

• Drowsiness or sedation

• Dizziness or fainting

• Dry mouth

• Constipation

• Increased appetite and weight gain

Serious Side Effects:

• Tardive dyskinesia (involuntary facial/muscle movements)

• Neuroleptic Malignant Syndrome (fever, stiff muscles, confusion)

• High blood sugar or cholesterol

• Low white blood cell count

• Suicidal thoughts (especially in youth)

Drug Interactions

Avoid combining Seroquit 50 mg with:

• MAO inhibitors or other antipsychotics

• CNS depressants (e.g., alcohol, benzodiazepines, opioids)

• Grapefruit juice (affects drug metabolism)

Precautions

• Not approved for dementia-related psychosis (increased risk of death)

• Use with caution in people with:

  • Diabetes

  • Heart conditions

  • Liver impairment

  • Seizure disorders

• Avoid sudden discontinuation — taper gradually

Storage Information

• Store at 15–30°C (room temperature)

• Keep away from moisture, heat, and direct sunlight

• Keep out of reach of children and pets

Availability in the US and Australia

• US: Quetiapine is sold as Seroquel and generic quetiapine. Seroquit may be an alternative brand not commonly marketed in the U.S.

• Australia: Available as Seroquel, and may be sold under other brand names like Seroquit in some pharmacies.

Frequently Asked Questions (FAQs)

1. Is Seroquit 50 mg used for sleep?

Yes, due to its sedative properties, it is sometimes prescribed off-label for insomnia, but long-term use just for sleep is not recommended.

2. Does it cause weight gain?

Yes, weight gain and increased appetite are common side effects, especially with extended use.

3. How quickly does it work?

You may feel sedation within hours, but antipsychotic or mood effects take 1–2 weeks or longer.

4. Can I drive while taking Seroquit 50 mg?

Avoid driving or operating machinery until you know how it affects you — drowsiness is common.

5. Is it habit-forming?

Seroquit is not addictive, but sudden withdrawal can cause symptoms. Always taper under medical guidance.